"...Here is J.F.’s report:
This morning, I read a report on augmentation of antidepressants.
It seems folks who get a little better, but not a lot better on an antidepressant may improve if a drug in the class of second generation antipsychotics is added.
Three of these drugs have been tested, with pretty much equivalent benefit – quetiapine, aripiprazole, and brexpiprazole.
As the names suggest, the last two are very similar in chemical structure.
– quetianpine and aripiprazole are available in cheap generic for. Brexpiprazole is not, it’s sold only as branded Rexulti.
– shortly after reading the piece, I walked past the waiting room TV which was playing an ad urging folks to “ask your doctor about Rexulti”.
– lowest costs for a month’s supply in my neighborhood, courtesy of goodrx.com:
- quetiapine – $6.80
- aripiprazole – $22.60
- Rexulti – $1,120.20 (!)
– so the ad is urging folks to “ask their doctor” about a drug that is 16,473% more expensive than a similar drug that may work just as well.
Thank you, J.F.
There you have it in a nutshell: U.S. Sickcare is organized to maximize profits by any means available..."
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